Mental DailyMental Daily
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Aa
Mental Daily
Aa
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • Opinion
Search
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Follow US
  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store
© 2022 - Mental Daily. All Rights Reserved.
Clinical

New research shows how type 2 diabetes may be linked to Alzheimer’s disease

Staff Writer
Staff Writer 1 year ago
Updated 2021/09/29 at 12:11 AM
Share
SHARE

Neuroscientists at the University of Nevada have shown how type 2 diabetes may be linked to Alzheimer’s disease.

Published online in Communications Biology, researchers determined that chronic hyperglycemia disrupts working memory performance, impacting working memory networks.

“It is thought that chronic hyperglycemia leads to neuroinflammation and tau hyperphosphorylation in the hippocampus leading to cognitive decline, but effects on hippocampal network activity are unknown,” according to the findings.

“A sustained hyperglycemic state was induced in otherwise healthy animals and subjects were then tested on a spatial delayed alternation task while recording from the hippocampus and anterior cingulate cortex (ACC). Hyperglycemic animals performed worse on long delay trials and had multiple electrophysiological differences throughout the task.”


When investigating the link between type 2 diabetes and Alzheimer’s disease, researchers uncovered that the hippocampus and the anterior cingulate cortex, both crucial in memory formation and retrieval, had been hypersynchronized.

“We found increased delta power and decreased theta power in the hippocampus, which led to altered theta/delta ratios at the end of the delay period,” the authors explained in their findings.

“Cross frequency coupling was significantly higher in multiple bands and delay period hippocampus-ACC theta coherence was elevated, revealing hypersynchrony.”

“Future work is needed to disentangle how insulin levels affect network dysfunction and working memory impairments, where insulin levels are controlled after streptozotocin treatment,” the authors also mentioned.

The study was funded by a grant from the National Institute on Aging.

Photo: Technology Networks

You Might Also Like

New study explores test that can detect Alzheimer’s years before diagnosis

New research explores the association between viral infection and Alzheimer’s disease

Prenatal exposure to pollution may be linked to lower cognitive scores in infants

Researchers unveil new drug candidate to help treat adrenoleukodystrophy

New research finds Alzheimer’s risk factors affect males and females very differently

TAGGED: Alzheimer's disease, cognition, memory, type 2 diabetes
Staff Writer September 28, 2021
Share this Article
Facebook Twitter Whatsapp Whatsapp Email Print
Previous Article Increasing consumption of fruits and vegetables in children may enhance mental health
Next Article Anticonvulsant levetiracetam may also improve learning and memory in patients with Alzheimer’s

Recommended

Clinical

New study explores test that can detect Alzheimer’s years before diagnosis

1 Min Read
Health

New research explores the association between viral infection and Alzheimer’s disease

1 Min Read
Clinical

Prenatal exposure to pollution may be linked to lower cognitive scores in infants

1 Min Read
Clinical

Researchers unveil new drug candidate to help treat adrenoleukodystrophy

1 Min Read
//

We are a trusted online source for research news and resources on all aspects of the mind and human behavior.

Verticals

  • Clinical
  • Health
  • Social
  • I/O
  • Opinion

Social

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Links

  • About
  • Contact
  • The Editor
  • Terms & Conditions
  • Privacy Policy
Follow US

© 2022 Mental Daily. All Rights Reserved.

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?