Mental DailyMental Daily
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • The Discussion
    • My Bookmarks
Aa
Mental Daily
Aa
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • Opinion
Search
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • The Discussion
    • My Bookmarks
Follow US
  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store
© 2022 - Mental Daily. All Rights Reserved.
Health

How certain microRNAs may serve as biomarkers for mild traumatic brain injury

Staff Writer
Staff Writer 1 year ago
Updated 2021/05/12 at 6:20 PM
Share
SHARE

Researchers from the University of Eastern Finland uncovered how certain microRNAs could serve as diagnostic biomarkers for mild traumatic brain injury.

Their results were released in the International Journal of Molecular Sciences.

For researchers, diagnosing mild traumatic brain injury brings about a challenge, especially considering that many patients do not exhibit visual structural damage to the brain. Thus making it difficult to detect by traditional imaging methods or computer tomography.

As part of the new research, the Finnish team examined microRNAs that could be regarded as biomarkers for the diagnosis of mild traumatic brain injury.

Blood plasma samples were collected from an animal model following a mild and severe form of traumatic brain injury.

“We hypothesized that acutely altered plasma miRNAs could serve as diagnostic biomarkers both in the lateral fluid percussion injury (FPI) model and clinical mTBI,” the findings read.

“We performed plasma small RNA-sequencing from adult male Sprague–Dawley rats at 2 days post-TBI, followed by polymerase chain reaction (PCR)-based validation of selected candidates.”

Out of their findings emerged two biomarkers of interest: the miRNAs miR-9a-3p and miR-136-3p. When both biomarkers were analyzed in blood samples of patients with traumatic brain injury, it was established that elevated levels of either biomarker led to the identification of patients with the condition.

“… plasma miR-9-3p and miR-136-3p were identified as promising biomarker candidates for mTBI requiring further evaluation in a larger patient population,” the study concluded.

Photo: Pinterest

You Might Also Like

Study finds no structural brain change during mindfulness-based stress training

New research of vegetarian diets uncovered similar growth and nutrition as meat consumers

Being overweight during childhood may raise the risk of type 1 diabetes

Over a million less smokers projected after U.S. ban on menthol cigarettes: study

Study probes the communication between physicians and patients regarding e-cigarette use

TAGGED: microRNAs, mild traumatic brain injury, neuroscience
Staff Writer February 15, 2021
Share this Article
Facebook Twitter Whatsapp Whatsapp Email Print
Previous Article The risk of childhood asthma may be heightened by fetal exposure to antibiotics in mid to late pregnancy
Next Article 14 percent of immigrant members have made the 117th Congress very diverse

Recommended

Clinical

Study finds no structural brain change during mindfulness-based stress training

1 Min Read
Health

New research of vegetarian diets uncovered similar growth and nutrition as meat consumers

1 Min Read
Health

Being overweight during childhood may raise the risk of type 1 diabetes

1 Min Read
Health

Over a million less smokers projected after U.S. ban on menthol cigarettes: study

1 Min Read
//

We are a trusted online source for research news and resources on all aspects of the mind and human behavior.

Verticals

  • Clinical
  • Health
  • Social
  • I/O
  • Opinion

Social

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Links

  • About
  • Contact
  • Terms & Conditions
  • Privacy Policy
Follow US

© 2022 Mental Daily. All Rights Reserved.

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?