A team of researchers at Karolinska Institutet uncovered a mode of action explaining how long-term use of proton pump inhibitors may increase the risk of dementia.
In their findings, researchers comprehensively examined the accuracy and efficacy of biomarkers for the diagnosis of Alzheimer's, after reviewing three separate tests.
The findings, released online in Cerebral Cortex, featured the use of laboratory rodents with hereditary and cumulative hearing loss beginning in early adulthood.
For the study, researchers examined patterns of protein expressed in over 2,000 human brain and close to 400 cerebrospinal fluid samples belonging to individuals with and without the presence of neurodegeneration.
According to their findings, a correlation between MBI and early Alzheimer's disease pathology was demonstrated for the first time through a set of cognitive assessments and brain imaging tests.
The findings were part of the Anti-Amyloid Treatment in Asymptomatic Alzheimer disease (A4) Study, an ongoing prevention trial with a primary objective of probing normal older adults with increased brain amyloid.
A team of researchers at the University of California, San Diego unveiled a new PHGDH gene discovery that could pave the way for the development of a blood test for detecting Alzheimer's
A research team funded by the National Institutes of Health made advancements in the development of a blood test able to predict Alzheimer's disease.