Mental DailyMental Daily
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Aa
Mental Daily
Aa
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • Opinion
Search
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Follow US
  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store
© 2022 - Mental Daily. All Rights Reserved.
Clinical

Researchers discover potential therapeutic target for treatment-resistant epilepsy

Staff Writer
Staff Writer 3 months ago
Updated 2023/03/19 at 11:14 AM
Share
SHARE

The Tufts University School of Medicine team and their collaborators have discovered a small molecule that shows promise as a treatment for people with epilepsy whose seizures have become resistant to benzodiazepine drugs.

Cell Reports Medicine posted the results of the study on the internet on March 7. The study was conducted on cultured human cells and rodents.

Researchers wanted to find brain areas where abnormal signals could be repaired. Their attention was directed toward a potassium chloride co-transporter known as KCC2. In a healthy brain, KCC2 pumps chloride out of nerve cells to slow down excessive firing of neurons.

Researchers found that when Compound 350 was given to rodents with drug-resistant seizures alongside benzodiazepine, the rodents’ seizure activity decreased.

What researchers stated: “These findings demonstrate that KCC2 activation is a promising strategy to terminate BDZ-resistant seizures and limit the associated neuronal injury.”

You Might Also Like

Study suggests semaglutide may reduce alcohol intake and relapse-like drinking

Cognitive disorders may develop due to molecular overreaction to ribosome stalling

Researchers have uncovered hints as to why immune cells appear to cause brain damage

Researchers use AI to generate video from brain activity

New research emphasizes the need for neuroscientific evidence in rape trials

TAGGED: KCC2, epilepsy, neuroscience
Staff Writer March 19, 2023
Share this Article
Facebook Twitter Whatsapp Whatsapp Email Print
Previous Article Researchers investigate how native languages shapes our brain wiring
Next Article People from varying cultures may be better at addressing the effects of frontotemporal dementia

Recommended

Clinical

Study suggests semaglutide may reduce alcohol intake and relapse-like drinking

3 Min Read
Clinical

Cognitive disorders may develop due to molecular overreaction to ribosome stalling

2 Min Read
Clinical

Researchers have uncovered hints as to why immune cells appear to cause brain damage

1 Min Read
Clinical

Researchers use AI to generate video from brain activity

2 Min Read
//

We are a trusted online source for research news and resources on all aspects of the mind and human behavior.

Verticals

  • Clinical
  • Health
  • Social
  • I/O
  • Opinion

Social

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Links

  • About
  • Contact
  • The Editor
  • Terms & Conditions
  • Privacy Policy
Follow US

© 2022 Mental Daily. All Rights Reserved.

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?