Experts have put forth more evidence that intracranial pressure plays a significant role in normal-tension glaucoma, which accounts for up to half of all glaucoma cases.
New research indicates that low intracranial pressure correlates with poor patient sight, particularly in the nasal zone.
The findings were published in Diagnostics.
“Growing evidence suggests that intracranial pressure (ICP) plays an important role in the pathophysiology of glaucoma, especially in normal-tension glaucoma (NTG) patients,” according to the study’s authors.
“Controversial results exist about ICP’s relationship to visual field (VF) changes. With the aim to assess the relationship between ICP and VF zones in NTG patients, 80 NTG patients (age 59.5 (11.6) years) with early-stage glaucoma were included in this prospective study.”
“Higher translaminar pressure difference was correlated with lower mean deviation and higher pattern standard deviation. Intracranial pressure was significantly associated with the lowest averaged pattern deviation values within the nasal visual field zone. These data support additional studies to reveal the mechanistic involvement of ICP in glaucoma pathophysiology, especially as a potential biomarker for NTG,” the findings concluded.
