Mental DailyMental Daily
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Aa
Mental Daily
Aa
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • Opinion
Search
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Follow US
  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store
© 2022 - Mental Daily. All Rights Reserved.
Clinical

Amyloid protein in the liver may lead to the development of Alzheimer’s disease

Staff Writer
Staff Writer 1 year ago
Updated 2021/09/15 at 1:14 AM
Share
SHARE

According to a study published in PLOS Biology, amyloid protein from the liver may lead to the development of Alzheimer’s disease in the brain.

The study was conducted by John Mamo and his colleagues at Curtin University in Australia.

For researchers, their study aimed at examining if the peripheral metabolism of amyloid-beta increases the risk of Alzheimer’s disease.

“In this study, we report that genetic modification of C57BL/6J mice engineered to synthesise human Aß only in liver (hepatocyte-specific human amyloid (HSHA) strain) has marked neurodegeneration concomitant with capillary dysfunction, parenchymal extravasation of lipoprotein-Aß, and neurovascular inflammation,” the authors explained in their findings.


“Moreover, the HSHA mice showed impaired performance in the passive avoidance test, suggesting impairment in hippocampal-dependent learning. Transmission electron microscopy shows marked neurovascular disruption in HSHA mice.”

In closing, the study provides ample causation of a lipoprotein-Aß /capillary axis for the development of Alzheimer’s disease.

“While further studies are now needed, this finding shows the abundance of these toxic protein deposits in the blood could potentially be addressed through a person’s diet and some drugs that could specifically target lipoprotein amyloid, therefore reducing their risk or slowing the progression of Alzheimer’s disease,” the authors affirmed.

You Might Also Like

Recalling sexual victimization may not be impaired by moderate alcohol intoxication

Research shows obesity-related neurodegeneration is similar to Alzheimer’s disease

New study explores test that can detect Alzheimer’s years before diagnosis

New research explores the association between viral infection and Alzheimer’s disease

Prenatal exposure to pollution may be linked to lower cognitive scores in infants

TAGGED: Alzheimer's disease, amyloid beta, cognition
Staff Writer September 14, 2021
Share this Article
Facebook Twitter Whatsapp Whatsapp Email Print
Previous Article American college students who vape may be at a higher risk of eating disorders
Next Article Study unveils a potentially new pathway for the treatment of seizures associated with autism

Recommended

Clinical

Recalling sexual victimization may not be impaired by moderate alcohol intoxication

2 Min Read
Clinical

Research shows obesity-related neurodegeneration is similar to Alzheimer’s disease

1 Min Read
Clinical

New study explores test that can detect Alzheimer’s years before diagnosis

1 Min Read
Health

New research explores the association between viral infection and Alzheimer’s disease

1 Min Read
//

We are a trusted online source for research news and resources on all aspects of the mind and human behavior.

Verticals

  • Clinical
  • Health
  • Social
  • I/O
  • Opinion

Social

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Links

  • About
  • Contact
  • The Editor
  • Terms & Conditions
  • Privacy Policy
Follow US

© 2022 Mental Daily. All Rights Reserved.

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?