“We conducted fecal microbiota transplantation from either young (3–4 months) or old (19–20 months) donor mice into aged recipient mice (19–20 months),” the Nature study states.
“Transplant of a microbiota from young donors reversed aging-associated differences in peripheral and brain immunity, as well as the hippocampal metabolome and transcriptome of aging recipient mice. Finally, the young donor-derived microbiota attenuated selective age-associated impairments in cognitive behavior when transplanted into an aged host,” the study also states.
“Our results reveal that the microbiome may be a suitable therapeutic target to promote healthy aging.”
Despite the findings, researchers caution more research is necessary for future work to be considered in human subjects.