Mental DailyMental Daily
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Aa
Mental Daily
Aa
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • Opinion
Search
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Follow US
  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store
© 2022 - Mental Daily. All Rights Reserved.
Clinical

Perinatal exposure to antidepressants linked to changes in sensory processing

Staff Writer
Staff Writer 4 years ago
Updated 2020/01/12 at 9:37 AM
Share
SHARE

Among pregnant women, the use of common antidepressants, like selective serotonin reuptake inhibitors (SSRIs), increased over the past few decades.

Although previous research have provided a confined understanding of changes in behavior and brain structure during prenatal and early life exposure to SSRIs, a new study, conducted on rodents, suggests exposure to antidepressants during pregnancy and the first weeks of life could lead to altered sensory processing later in adulthood. The findings were published in eNeuro.

Fluoxetine, an antidepressant of the selective serotonin reuptake inhibitor class, was administered to rodents to examine changes in brain activity during gestation and the first two weeks after birth.

By theory, SSRIs, like fluoxetine, involves the neurotransmitter serotonin as key to the treatment of depression.

“Epidemiological studies have found an increased incidence of neurodevelopmental disorders in populations prenatally exposed to selective serotonin reuptake inhibitors (SSRIs),” the findings state.

“Optical imaging provides a minimally invasive way to determine if perinatal SSRI exposure has long-term effects on cortical function. Herein we probed the functional neuroimaging effects of perinatal SSRI exposure in a fluoxetine-exposed (FLX) mouse model.”

In a resting state, optical imaging examination of the rodents’ brains determined fluoxetine induced abnormal brain activity in sensory areas.

“These results suggest a global loss of response signal amplitude in FLX versus controls,” the findings determined. “These findings indicate that perinatal SSRI exposure has long-term consequences on somatosensory cortical responses.”

You Might Also Like

Study boasts MDMA-assisted therapy for PTSD patients

How the brain is organized is revealed by the largest genetic study of brain structure to date

Study investigates the ethical implications of combining the analysis of ancient DNA and data from private genetic databases

New study reveals positive results from postpartum depression treatment Zuranolone

New study explores magic mushrooms for anorexia nervosa psychopathology

TAGGED: antidepressants, Fluoxetine, pregnancy, serotonin
Staff Writer December 17, 2019
Share this Article
Facebook Twitter Whatsapp Whatsapp Email Print
Previous Article A diet of high-sugar and refined carbohydrates could raise the risk of insomnia
Next Article Cognitive behavioral therapy might combat accelerated cellular aging for patients with social anxiety

Recommended

Clinical

Study boasts MDMA-assisted therapy for PTSD patients

1 Min Read
Clinical

How the brain is organized is revealed by the largest genetic study of brain structure to date

2 Min Read
Clinical

Study investigates the ethical implications of combining the analysis of ancient DNA and data from private genetic databases

3 Min Read
Clinical

New study reveals positive results from postpartum depression treatment Zuranolone

2 Min Read
//

We are a trusted online source for research news and resources on all aspects of the mind and human behavior.

Verticals

  • Clinical
  • Health
  • Social
  • I/O
  • Opinion

Social

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Links

  • About
  • Contact
  • The Editor
  • Terms & Conditions
  • Privacy Policy
Follow US

© 2022 Mental Daily. All Rights Reserved.

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?