Mental DailyMental Daily
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Aa
Mental Daily
Aa
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • Opinion
Search
  • Clinical
  • Health
  • I/O
  • Cybernetic
  • Social
  • More
    • Opinion
    • My Bookmarks
Follow US
  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store
© 2022 - Mental Daily. All Rights Reserved.
Clinical

Calcium channel blockers may reduce memory decline in Alzheimer’s

Staff Writer
Staff Writer 4 years ago
Updated 2019/09/11 at 6:44 PM
Share
SHARE

Calcium channel blockers, also known as calcium antagonists, might reduce the severity of memory decline in people with Alzheimer’s disease, according to new research released in Frontiers in Cellular Neuroscience.

Using a genetically-encoded fluorescent molecule, known as GCaMP6f, researchers at the University of Bristol were able to measure calcium ions within brain cells to get a better understanding of the neurodegenerative disease.

Researchers found an overload of calcium ions in diseased brain cells caused an overproduction of the L-type calcium channel. The channel allows for the flow of calcium ions into the cell, in which an increase may induce cognitive decline. L-type channel antagonists decreased the flow and restored the calcium ions to normal levels.

In another test, researchers utilized two separate odors paired with an electric shock to examine for any memory impairment. This test produced similar results, indicating that the overproduction of L-type channels was associated with memory deficits.

“L-type channels have been thought to have a role in AD for some time and this study shows a direct link between memory loss and L-type channel overproduction in brain cells,” said James Hodge, co-author of the study.

“Memory loss in Alzheimer’s disease (AD) is a highly distressing and difficult to treat symptom. Targeting the early changes in brain cell function – before they begin to degenerate – may be effective in treating memory loss.”

You Might Also Like

Childhood history of hyperactivity and impulsivity associated with a higher risk of socially isolation

Shortening of telomeres has been linked to indications of Alzheimer’s disease in brain imaging

People from varying cultures may be better at addressing the effects of frontotemporal dementia

Researchers discover potential therapeutic target for treatment-resistant epilepsy

Researchers investigate how native languages shapes our brain wiring

TAGGED: calcium channel blockers, Alzheimer's disease, dementia
Staff Writer September 11, 2019
Share this Article
Facebook Twitter Whatsapp Whatsapp Email Print
Previous Article Pupillary dilation may aid in identifying risk for Alzheimer’s
Next Article Study links multilingualism to a reduced risk of dementia

Recommended

Clinical

Childhood history of hyperactivity and impulsivity associated with a higher risk of socially isolation

2 Min Read
Clinical

Shortening of telomeres has been linked to indications of Alzheimer’s disease in brain imaging

2 Min Read
Clinical

People from varying cultures may be better at addressing the effects of frontotemporal dementia

1 Min Read
Clinical

Researchers discover potential therapeutic target for treatment-resistant epilepsy

1 Min Read
//

We are a trusted online source for research news and resources on all aspects of the mind and human behavior.

Verticals

  • Clinical
  • Health
  • Social
  • I/O
  • Opinion

Social

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Links

  • About
  • Contact
  • The Editor
  • Terms & Conditions
  • Privacy Policy
Follow US

© 2022 Mental Daily. All Rights Reserved.

  • Twitter
  • Facebook
  • Instagram
  • Inc. Profile
  • Google Play Store

Removed from reading list

Undo
Welcome Back!

Sign in to your account

Lost your password?