Dosulepin (or PROTHIADEN®) is mainly prescribed to treat major depressive disorder.
Class: Tricyclic (TCA)
FDA Approval: International Only (Europe, Asia, Australia, New Zealand)
Dosage Forms: 25 mg, 75 mg
Biological Half-life: 14.4–23.9 hours
Side Effects: Dizziness, blurred vision, dry mouth, nausea, confusion, tachycardia, hypotension, arrhythmias, appetite changes, anxiety, urinary retention, extrapyramidal symptoms, increased suicide risk
Routes of Administration: Oral
Pregnancy Category: C (AU)