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Clozaril (clozapine)

Clozapine (or CLOZARIL®) is mainly prescribed to treat treatment-resistant schizophrenia.

FDA Approval: 2015

Dosage Forms: 12.5 mg, 25 mg, 50 mg, 100 mg, 200 mg, 300 mg, 400 mg, 500 mg, 600 mg, 700 mg, 800 mg, 900 mg

Biological Half-life: 6-26 hours

Side Effects: Constipation, bed-wetting, muscle stiffness, tremors, dizziness, orthostatic hypotension, hyperglycemia, weight gain

Serious Risks: Low white blood cells (agranulocytosis), myocarditis, gastrointestinal hypomotility

Routes of Administration: Oral

Pregnancy Category: B (US)

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