Clomipramine (or ANAFRANIL®) is mainly prescribed to treat major depressive disorder, obsessive-compulsive disorder, trichotillomania, panic disorder, and chronic pain.
Class: Tricyclic (TCA)
FDA Approval: 1989
Dosage Forms: 25 mg, 50 mg, 75 mg
Biological Half-life: 19-37 hours
Side Effects: Dry mouth, constipation, loss of appetite, sleepiness, weight gain, sexual dysfunction, mania, increased suicide risk
Routes of Administration: Oral, IV
Pregnancy Category: C (US)